Merck and Moderna Launch Phase 3 Trial for mRNA-4157 Neoantigen Therapy Plus Pembrolizumab in NSCLC
INTerpath-009 investigates the treatment for patients with resectable stage 2, 3A or 3B non–small cell lung cancer.
Researchers Find Lack of Communication for Lung Cancer Screenings Among High-Risk Individuals
Less than 16% of high-risk lung cancer individuals have heard or discussed lung cancer screenings with a health care provider.
Oral Semaglutide Reduces Risk of MACE for Patients With Type 2 Diabetes
Oral semaglutide had a safe and well-tolerated profile for individuals with type 2 diabetes, which is in line with those previously reported for the drug in other trials.
What to Know About E Coli Outbreak Linked to McDonald’s Quarter Pounders
Pharmacists will likely be the first contact for many affected patients, and they should be able to provide evidence-based advice on how to manage their infection.
New Human Case of H5N1 Bird Flu Confirmed in Missouri, CDC Reports
Despite the new human case, which is not known to be related to animal exposure, the CDC emphasizes that risk to the general public remains low.
FDA Authorizes New Drug Application For Trial to Evaluate Treatment for Long COVID
Bezisterim, an anti-inflammatory insulin sensitizer, will be authorized to proceed to a phase 2 clinical trial.
Climate Variability, Extremes Allow Emergence and Propagation of Cholera Strains
The researchers found that unusual and dramatic changes in weather as well as heavy rainfall helped aid in the pathogen’s evolutionary change.
Study Finds Intermittent Fasting May Offset Alzheimer Disease Risk, Support Treatment Goals
The study may serve as a foundation for future investigation regarding dietary recommendations to support the treatment of Alzheimer disease.
Researchers Identify a Potential Therapeutic Target for Multiple Sclerosis
The findings show that inhibiting connexin 43 significantly improves multiple sclerosis symptoms in an experimental mouse model.
CDC Recommends International Travelers Receive MMR Vaccination 2 Weeks Prior to Travel
The CDC says that even if travel is less than 2 weeks away, unvaccinated individuals should still receive a dose of the measles, mumps, and rubella vaccine for protection against the disease.
Analysis Determines Body Dysmorphic Disorder Is the Most Common in Adolescent Girls
The findings also demonstrate that body dysmorphic disorder is also associated with high levels of comorbid psychopathology, risk, and psychosocial impairment.
Study Finds Gender and Racial Disparities in Youth Psychiatric Inpatient Admissions
The authors emphasize that these findings suggest a need for targeted resources that help reduce boarding and promote equitable access to care.
Exploring the Connection Between Orange Peels, Gut Metabolism, and Heart Health
Study shows that orange peel extract may reduce risk of heart disease and adverse cardiovascular events.
Study Finds Association Between Sodium Intake and Risk of Atopic Dermatitis
Reducing sodium intake is associated with decreased risk of atopic dermatitis (AD) and flares.
Study Finds AI Models May Help Accurately Assess PTSD in Women After a Traumatic Childbirth
The authors note that this finding may have promise for use in assessing mental health conditions and improving patient outcomes.
FDA Accepts Application for 5-in-1 Meningococcal Vaccine Candidate
The 5-in-1 meningococcal ABCWY vaccine candidate has an assigned Prescription Drug User Fee Act action date of February 14, 2025.
Study Shows Diabetes, Pollution, Alcohol Intake Related to Onset of Cognitive Decline
A study about modifiable risk factors on a “weak spot” in the brain network found that diabetes, pollution, and alcohol were most likely to contribute to dementia disorders.
FDA Issues Letters to 6 Companies for Unapproved, Misbranded OTC Analgesic Products
The agency warns consumers against using these products, which are marketed for topical use to relieve pain associated with cosmetic procedures.
Study: Lebrikizumab Demonstrates Improvements in Atopic Dermatitis for Patients of Color
The efficacy data are consistent with other phase 3 studies, reinforcing lebrikizumab's potential as a first-line treatment across a range of skin tones.
Significant Events Throughout Life Increase Chances For Anxiety, Depression, and Cognitive Decline
The findings also indicated that individuals who experienced significant adverse events in childhood were approximately 17% more likely to experience adverse events in adulthood.
Environmental Toxin BPA Affects Gut Microbial Communities in Children
Children with normal weight had different community relationships compared to children with overweight or obesity.
Data From OUtMATCH Study Show Benefits of Xolair for Common Food Allergies
The data follow the FDA approval of omalizumab for the reduction of allergic reactions, including anaphylaxis, that can occur after exposure to 1 or more foods.
FDA Approves Omalizumab to Reduce Food-Based Allergic Reactions in Adult and Pediatric Patients
This marks omalizumab’s fourth FDA-approved indication for allergic and inflammatory conditions, such as severe persistent allergic asthma, with its initial approval being in 2003.
Gargling With Mouthwash Can Improve Oral Environment, Reduce HbA1c in Adults with Type 2 Diabetes
Mouthwash that contains chlorhexidine gluconate was especially effective at improving hyperglycemic status in younger patients with diabetes.
Black Women Experiencing Racism in 3 Categories Have Increased Risk of Coronary Heart Disease
Vitamin K Supplementation May Improve Insulin Resistance in Older Patients With Type 2 Diabetes
Inadequate levels of zinc, vitamin D, vitamin E, and vitamin B were also associated with risk of diabetes or diabetes-related complications.
Patients With Migraines Often Experience Stigma Related to Symptoms
Migraines are not a one-size-fits-all condition, and there is no one-size-fits-all solution.
Study: A Plant-Based Diet Could Reduce COVID-19 Infection
Individuals that lived on a majority plant-based or vegetarian/vegan diet were 39% less likely to be infected with COVID-19.
FDA Approves New LASIK Device Teneo for Vision Correction Surgery
Teneo Excimer Laser Platform is a new laser assistance in situ keratomileusis for vision correction surgery for those who have myopia and myopic astigmatism.
Thinking Beyond Technology: Why a Holistic Approach Is a Better Way to Fight Drug Diversion
Although we have made strides in adopting technology to combat diversion, the uptake of advanced technology is slow and steady.