Can Coffee Drinking Improve Survival in HIV/HCV Patients?

Daily coffee consumption can reduce risk of all-cause mortality in patients who are co-infected with HIV and hepatitis C virus (HCV) by half, according to a recently-published study in theJournal of Hepatology.

drinking at least 3 cups of coffee per day halved all-cause mortality risk in patients who are coinfected with HIV and HCV, likely because of coffee’s known anti-inflammatory and liver-protective properties.

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For the study, the researchers gathered data from a 5-year follow up of 1028 patients who were coinfected with HIV and HCV, enrolled in the French national ANRS CO13-HEPAVIH cohort. At the start of the study, 1 in 4 patients reported drinking at least 3 cups of coffee daily. Over the course of the study period, 77 deaths occurred, almost half of which were attributable to hepatitis C.

Previous studies have also linked coffee consumption to a reduced mortality risk in healthy individuals

Upon further analysis, the researchers discovered that consuming at least 3 cups of coffee each day was linked to a 50% reduction in mortality risk, even after taking into account other factors such as HCV clearance, having a steady partner, and not smoking.

The researchers noted that the findings highlight the importance of behaviors on reduced mortality risk, especially in patients with HIV and HCV. Certain behavioral changes, such as coffee consumption and not smoking, can positively impact survival in this population, the researchers concluded, and health care professionals should promote healthy behaviors in these patients after HCV clearance.

Reference

Carrieri MP, Protopopescu C, Marcellin F, et al. Protective benefit of coffee consumption on all-cause mortality of French HIV-HCV co-infected patients.

. 2017. Doi:

J Hepatol10.1016/j.jhep.2017.08.005

In the 5-year study, the researchers found that